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Agreement of the Heidelberg Retina Tomograph II macula edema module with fundus biomicroscopy in diabetic maculopathy

机译：海德堡视网膜断层扫描II黄斑水肿模块与糖尿病黄斑病变眼底生物显微镜的协议

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Objectives: To estimate the agreement between the macular edema maps (MEMs) of the Retina Module of the Heidelberg Retina Tomograph II (Heidelberg Engineering, Heidelberg, Germany) and contact lens fundus biomicroscopy (FB) and to assess the influence of combining MEM data with the results of short-wavelength automated perimetry (SWAP) and fluorescein angiography (FA) on diagnostic test performance. Design: Prospective, observational case series. Methods: Twenty patients (20 eyes) with diabetic retinopathy with or without clinically manifest macular edema (11 and 9 eyes, respectively) were enrolled. All patients underwent full ophthalmologic examination and also MEM assessment, SWAP, and FA. Results: Using FB as the "gold standard," the agreement between the MEMs and FB was very good (Kendall coefficient of concordance, 0.80). Macular edema maps showed good agreement with FA and SWAP (Kendall coefficient, 0.64 and 0.65). Virtually all of the edematous areas detected with MEM but not seen clinically had decreased sensitivity on SWAP and/or fluorescein leakage. Conclusions: Macular edema maps demonstrated very good agreement with FB. Combining the results of FA and SWAP with those of the MEMs provided supporting evidence of concomitant blood-retinal barrier leakage and visual dysfunction, respectively, in areas of early retinal thickening. Prospective studies are ongoing to fully assess the diagnostic test performance of MEMs in the detection of early and progressive diabetic macular edema. ©2006 American Medical Association. All rights reserved.
机译：目的：评估海德堡视网膜断层成像II（Heidelberg Engineering，Heidelberg，Germany）的海德堡视网膜断层成像II的视网膜模块的黄斑水肿图（MEMs）与隐形眼镜眼底生物显微镜（FB）之间的一致性，并评估将MEM数据与短波自动视野检查（SWAP）和荧光素血管造影（FA）对诊断测试性能的结果。设计：前瞻性观察病例系列。方法：招募了20例（20眼）糖尿病性视网膜病，有或没有临床表现的黄斑水肿（分别为11眼和9眼）。所有患者均接受了全面的眼科检查以及MEM评估，SWAP和FA。结果：使用FB作为“金标准”，MEM与FB之间的一致性非常好（Kendall一致性系数为0.80）。黄斑水肿图显示与FA和SWAP吻合良好（Kendall系数分别为0.64和0.65）。几乎所有用MEM检测到但临床上未见到的水肿区域对SWAP和/或荧光素渗漏的敏感性均降低。结论：黄斑水肿图显示与FB非常吻合。将FA和SWAP的结果与MEM的结果相结合，分别提供了视网膜早期增厚区域同时发生的血视网膜屏障泄漏和视觉功能障碍的证据。正在进行前瞻性研究，以全面评估MEM在检测早期和进行性糖尿病性黄斑水肿中的诊断测试性能。 ©2006美国医学会。版权所有。

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